RNA Details
Disease Name
atrial fibrillation
Tissue
heart
RNA Symbol
mir-1202
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
qRT-PCR;CCK-8 assays;western blot
Target
nNOS
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
"MiRNA-1202 promotes the TGF-beta1-induced proliferation, differentiation and collagen production of cardiac fibroblasts by targeting nNOS"
Year
2021
Function
MiR-1202 promotes human cardiac fibroblasts transformation to a pro-fibrotic phenotype by targeting nNOS through activating the TGF-beta1/Smad2/3 pathway.